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Therapeutic strategies targeting this axis (Figure 2), such as BH4 supplementation, NOX inhibitors, and lifestyle modifications (e.g., exercise, Mediterranean diet), aim to restore redox balance and endothelial function, though their efficacy varies by HTN stage and comorbidities
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Volume:Single 10mg vial
Clin J Am Soc Nephrol 2011;6:30–39
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