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Considering that the use of NSAIDs, paracetamol, and opioid analgesics represents the main therapeutic choice in this field for managing the nociceptive component of pain, whereas the neuropathic component is generally managed with agents like gabapentinoids (e.g., gabapentin, pregabalin) or certain antidepressants (e.g., amitriptyline, duloxetine), it is well known that these drugs are associated with significant side effects that limit their use for prolonged periods
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[DOI] [PubMed] [Google Scholar] Chattopadhyaya I., Gupta S., Mohammed A., Mushtaq N., Chauhan S., Ghosh S