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In breast cancer models, tumour-derived adrenomedullin (ADM), a hypoxia-inducible peptide, drives UCP1 expression in adjacent adipocytes through paracrine signalling [348]
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The results of the MTT assay indicated that the IC 50 values for simvastatin and the costimulation of Ncl-N87 cells with simvastatin and erastin were 19.5 μM and 10.5 μM, respectively
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