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FOXO1, a pro-apoptotic transcription factor in cartilage, was investigated and it was found that silencing of FOXO1 in chondrocytes resulted in a significant reduction in the mRNA levels of pro-apoptotic genes caspase-3, caspase-8, caspase-9 and TRAIL
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Xu X., Pang Y., and Fan X., “Mitochondria in Oxidative Stress, Inflammation and Aging: From Mechanisms to Therapeutic Advances,” Signal Transduction and Targeted Therapy 10, no
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