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Two double-blind placebo-controlled studies in patients with chronic insomnia reached opposite conclusions: one, in 14 patients, reported that sleep efficiency and daytime function reached the levels of normal controls, the other, in 16 patients, reported weak effects that it said could partly reflect a change in the placebo group and concluded the compound was unlikely to be of major benefit
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According to the review performed by Benvenga, the introduction of treatment with l-carnitine may be beneficial in hyperthyroid patients, especially symptomatic individuals, who need to take lower doses of antithyroid drugs (2 g/day)