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This overview is intended to contextualize existing findings, without suggesting subtype-specific therapeutic applications (Table 1)
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In Mrp3 knockout mice, the levels of resveratrol-3-glucuronide were up to 10-fold lower in plasma and urine (van de Wetering et al., 2009), and levels of morphine-3-glucuronide were up to 50-fold lower in plasma (Zelcer et al., 2005), owing to the lack of Mrp3 in the basolateral membrane of the enterocytes
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