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In a study, paclitaxel was loaded into human normal pancreatic duct cell line hTERT-HPNE-derived EVs and enhanced its effect in pancreatic ductal adenocarcinoma (PDAC) cells through a clathrin-dependent endocytosis pathway
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As an apremilast, DMF also exhibits strong anti-inflammatory and immunomodulatory effects and was tested in a laboratory to evaluate its role in ameliorating basal inflammation and metabolic disturbances (79)